Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803194 | 0.85 | AVPR1A (0.45) | AVPR1AAVPR2SPROPRL1OXTR | |
| SCHEMBL16390887 | 0.76 | ALDH1A1 (0.39) | AVPR1AALDH1A1USP2TSHRKDM4E | |
| SCHEMBL2799905 | 0.76 | AVPR1A (0.46) | AVPR1AAVPR2SPROPRL1OXTR | |
| SCHEMBL16390878 | 0.73 | ALDH1A1 (0.39) | ALDH1A1USP2TSHRKDM4EHPGD | |
| SCHEMBL2803834 | 0.72 | RBP4 (0.40) | OPRL1ALDH1A1TSHR | |
| SCHEMBL16390772 | 0.72 | GSK3B (0.38) | ALDH1A1USP2TSHRKDM4EHPGD | |
| SCHEMBL2804011 | 0.72 | NPY5R (0.42) | AVPR1A | |
| SCHEMBL2801650 | 0.71 | AVPR1A (0.46) | AVPR1AAVPR2SPROPRL1OXTR | |
| SCHEMBL2801247 | 0.70 | IDO1 (0.39) | AVPR1AALDH1A1KDM4EHPGD | |
| SCHEMBL2802503 | 0.69 | CCR5 (0.34) | ALDH1A1USP2TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206714-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |