Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 8/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798663 | 0.92 | FAAH (0.42) | BRD4FAAHSYKOPRD1 | |
| SCHEMBL4618217 | 0.90 | FAAH (0.45) | BRD4FAAHSYKOPRD1 | |
| SCHEMBL2799815 | 0.82 | DAGLB (0.39) | BRD4DAGLB | |
| SCHEMBL3428136 | 0.79 | F2RL3 (0.38) | BRD4DAGLB | |
| SCHEMBL4924459 | 0.79 | BRD4 (0.38) | BRD4FAAHSYK | |
| SCHEMBL5735308 | 0.75 | SPHK2 (0.43) | — | |
| SCHEMBL3520472 | 0.75 | SPHK2 (0.43) | — | |
| SCHEMBL14089392 | 0.75 | CHRNB4 (0.41) | — | |
| SCHEMBL2797321 | 0.74 | CPT1A (0.36) | — | |
| SCHEMBL3282936 | 0.71 | ALDH1A1 (0.41) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168143-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168143-A1 | QUINAZOLINE DERIVATIVES | CCNI, NQO2, MKI67 | BRD4 205/4885FAAH 4290/4885SYK 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.