Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788992 | 0.75 | HTR2A (0.41) | HTR6 | |
| SCHEMBL27714402 | 0.72 | HTR2A (0.34) | SIGMAR1HTR6 | |
| SCHEMBL8959338 | 0.71 | HTR6 (0.31) | HTR6 | |
| SCHEMBL30995707 | 0.68 | MAOB (0.51) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL1051972 | 0.68 | MAOB (0.51) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL27788839 | 0.67 | HTR2A (0.34) | SIGMAR1HTR6 | |
| SCHEMBL27980204 | 0.67 | CYP2D6 (0.43) | HTR6 | |
| SCHEMBL28339720 | 0.66 | DRD2 (0.31) | HTR6 | |
| SCHEMBL27842888 | 0.65 | MAOB (0.44) | MAOAMAOBSIGMAR1BCHEADRA2B | |
| SCHEMBL27759010 | 0.65 | MAOB (0.44) | MAOAMAOBSIGMAR1BCHEADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622225-B | Methods for isolating propargylated aminoindans | TEVA PHARMA | 2015-04-15 | — | — | CN | claimed |
| CN-101622225-B | Methods for isolating propargylated aminoindans | TEVA PHARMA | 2015-04-15 | — | — | CN | disclosed |