Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959338 | 0.80 | HTR6 (0.31) | HTR2AHTR6 | |
| SCHEMBL18775716 | 0.69 | RET (0.36) | HTR2AHTR6RET | |
| SCHEMBL5150447 | 0.67 | HTR2A (0.38) | HTR2AHTR6RET | |
| SCHEMBL7197990 | 0.67 | HTR2A (0.38) | HTR2AHTR6RET | |
| SCHEMBL1680358 | 0.67 | HTR2A (0.38) | HTR2AHTR6RET | |
| SCHEMBL1680359 | 0.67 | RET (0.38) | HTR2AHTR6RET | |
| SCHEMBL5370598 | 0.67 | HTR2A (0.34) | HTR2AHTR6RET | |
| SCHEMBL6700611 | 0.67 | POLB (0.39) | HTR2AHTR6RET | |
| SCHEMBL5718862 | 0.67 | RET (0.39) | HTR2AHTR6RET | |
| SCHEMBL4516491 | 0.67 | RET (0.42) | HTR2AHTR6RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622225-A | Methods for isolating propargylated aminoindans | TEVA PHARMA | 2010-01-06 | — | — | CN | claimed |
| CN-101622225-A | Methods for isolating propargylated aminoindans | TEVA PHARMA | 2010-01-06 | — | — | CN | disclosed |