SCHEMBL2801311

SCHEMBL2801311

Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)nc1NO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
MTOR P42345 2/20 0.53
ALDH1A1 P00352 2/20 0.53
TP53 P04637 2/20 0.53
THRB P10828 1/20 0.53
MDM2 Q00987 1/20 0.53
NCOA1 Q15788 1/20 0.53
NCOA3 Q9Y6Q9 1/20 0.53
GMNN O75496 1/20 0.53
NFKB1 P19838 1/20 0.53
DNMT1 P26358 1/20 0.53
THPO P40225 1/20 0.53
HTT P42858 1/20 0.53
RAB9A P51151 1/20 0.53
BLM P54132 1/20 0.53
HBB P68871 1/20 0.53
PMP22 Q01453 1/20 0.53
MAPT P10636 1/20 0.50
CDA P32320 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15011109 1.00 LMNA (0.53) LMNAMTORALDH1A1TP53THRB
SCHEMBL20668807 1.00 LMNA (0.53) LMNAMTORALDH1A1TP53THRB
SCHEMBL20668805 1.00 LMNA (0.53) LMNAMTORALDH1A1TP53THRB
SCHEMBL15011373 0.90 LMNA (0.53) LMNAMTORALDH1A1TP53THRB
SCHEMBL14441078 0.90 LMNA (0.53) LMNAMTORALDH1A1TP53THRB
SCHEMBL10187890 0.90 LMNA (0.53) LMNAMTORALDH1A1TP53THRB
SCHEMBL25565426 0.90 LMNA (0.42) LMNAMTORALDH1A1TP53THRB
SCHEMBL15010651 0.89 LMNA (0.55) LMNAMTORALDH1A1TP53THRB
SCHEMBL15010648 0.89 LMNA (0.55) LMNAMTORALDH1A1TP53THRB
Hydrogen Sulfide SCHEMBL28296750 0.88 LMNA (0.54) LMNAMTORALDH1A1TP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384740-B2 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2025-08-12 US claimed
CN-114450265-B Cationic lipids and uses thereof 菲克特生物科学股份有限公司 2024-12-24 CN claimed
US-20230373903-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS FACTOR BIOSCIENCE INC. 2023-11-23 US claimed
US-11814333-B2 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2023-11-14 US claimed
US-20230193207-A1 MESENCHYMAL STEM CELL THERAPIES FACTOR BIOSCIENCE INC. 2023-06-22 US claimed
US-20230193231-A1 ENGINEERED GENE-EDITING PROTEINS FACTOR BIOSCIENCE INC. 2023-06-22 US claimed
EP-4149252-A2 ENGINEERED GENE-EDITING PROTEINS Factor Bioscience Inc. (US) 2023-03-22 EP claimed
EP-4142744-A1 MESENCHYMAL STEM CELL THERAPIES Factor Bioscience Inc. (US) 2023-03-08 EP claimed
CN-115701285-A Mesenchymal stem cell therapy 菲克特生物科学股份有限公司 2023-02-07 CN claimed
US-20220106256-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS FACTOR BIOSCIENCE INC. 2022-04-07 US claimed
US-11242311-B2 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2022-02-08 US claimed
WO-2021231549-A2 ENGINEERED GENE-EDITING PROTEINS FACTOR BIOSCIENCE INC. (US) 2021-11-18 WO claimed
WO-2021222389-A1 MESENCHYMAL STEM CELL THERAPIES FACTOR BIOSCIENCE INC. (US) 2021-11-04 WO claimed
US-20210032192-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS NOVELLUS, INC. 2021-02-04 US claimed
US-10752576-B1 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2020-08-25 US claimed
US-10611722-B1 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2020-04-07 US claimed
US-20260144753-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2026-05-28 US disclosed
US-20260146264-A1 METHODS FOR REPROGRAMMING AND GENE EDITING CELLS FACTOR BIOSCIENCE INC. (US) 2026-05-28 US disclosed
US-20030087873-A1 Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation PHARMASSET, INC. 2003-05-08 US disclosed
WO-2002032920-A2 MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION PHARMASSET LIMITED (BB) 2002-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032192-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-20220106256-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-10752576-B1 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-20230373903-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-12384740-B2 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-20260144753-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS PLTP, SLC7A1, PCTP LMNA 403/4885MTOR 2930/4885ALDH1A1 3704/4885
US-10611722-B1 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-20260146264-A1 METHODS FOR REPROGRAMMING AND GENE EDITING CELLS ZMYND8, STING1, DCLRE1A LMNA 2027/4885MTOR 3404/4885ALDH1A1 1643/4885
US-11814333-B2 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-11242311-B2 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 LMNA 264/4885MTOR 4508/4885ALDH1A1 4835/4885
US-20030087873-A1 Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation SLC29A1, PNP, SLC29A2 LMNA 1076/4885MTOR 3184/4885ALDH1A1 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.