SCHEMBL28013483

SCHEMBL28013483

O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1-c1cccs1

nearest known ligand 0.75

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 5/20 0.75
PYGM P11217 3/20 0.58
TK2 O00142 2/20 0.54
SLC28A1 O00337 1/20 0.53
SLC28A2 O43868 1/20 0.53
SLC29A1 Q99808 1/20 0.53
SLC28A3 Q9HAS3 1/20 0.53
ADK P55263 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10429996 0.83 P2RY2 (0.62) P2RY2PYGMTK2
SCHEMBL28937870 0.83 P2RY2 (0.74) P2RY2PYGMTK2SLC28A1SLC28A2
SCHEMBL2577658 0.83 P2RY2 (0.74) P2RY2PYGMTK2SLC28A1SLC28A2
SCHEMBL1635432 0.81 LMNA (0.61) P2RY2TK2
SCHEMBL30698162 0.81 LMNA (0.61) P2RY2TK2
SCHEMBL1756143 0.81 PYGM (0.59) P2RY2PYGMTK2SLC28A1SLC28A2
SCHEMBL1756141 0.81 PYGM (0.59) P2RY2PYGMTK2SLC28A1SLC28A2
SCHEMBL8936552 0.81 LMNA (0.61) P2RY2TK2
SCHEMBL1635430 0.81 LMNA (0.61) P2RY2TK2
SCHEMBL9029499 0.80 P2RY2 (0.51) P2RY2PYGMTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104706654-A Application of near ultraviolet irradiation 4-sulf-5-thienyl uridine in resisting melanin tumor cells and colon cancer cells UNIV DALIAN 2015-06-17 CN disclosed