Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.51 |
| ▸ | TK2 | O00142 | 9/20 | 0.43 |
| ▸ | PYGM | P11217 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030185 | 1.00 | P2RY2 (0.51) | P2RY2TK2PYGM | |
| SCHEMBL8539642 | 0.82 | TK2 (0.44) | P2RY2TK2PYGM | |
| SCHEMBL28013483 | 0.80 | P2RY2 (0.75) | P2RY2TK2PYGM | |
| SCHEMBL10643570 | 0.77 | TK2 (0.45) | TK2 | |
| SCHEMBL10647357 | 0.77 | TK2 (0.45) | TK2 | |
| SCHEMBL10646803 | 0.75 | DNPH1 (0.40) | P2RY2TK2 | |
| SCHEMBL10642490 | 0.75 | DNPH1 (0.40) | P2RY2TK2 | |
| SCHEMBL10644559 | 0.74 | TK2 (0.37) | P2RY2TK2 | |
| SCHEMBL10647174 | 0.74 | TK2 (0.37) | P2RY2TK2 | |
| SCHEMBL8936593 | 0.73 | P2RY2 (0.42) | P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0691333-A2 | Pyrimidine derivatives, process for their preparation and their use as precursors | Medivir Aktiebolag (SE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |