Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019813 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL27456060 | 0.78 | EPHX1 (0.46) | EPHX1HPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1620163 | 0.75 | EPHX1 (0.43) | EPHX1HPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28014188 | 0.73 | HPGD (0.47) | HPGDPOLBALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL28019225 | 0.72 | ALDH1A1 (0.41) | EPHX1ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL27938805 | 0.71 | ALDH1A1 (0.42) | POLBALDH1A1MAPTKDM4EGAA | |
| SCHEMBL28819013 | 0.70 | NPC1 (0.48) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL10691288 | 0.70 | EPHX1 (0.45) | EPHX1HPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8074109 | 0.70 | ALDH1A1 (0.52) | EPHX1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL28176461 | 0.67 | ALDH1A1 (0.69) | EPHX1HPGDPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592059-B | 3-acylhydrazone diphenylurea derivative and its preparation method and application | 青岛农业大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104610142-A | 3-bishydrazide diphenylurea derivative, and preparation method and application of 3-bishydrazide diphenylurea derivative | UNIV QINGDAO AGRICULTURAL | 2015-05-13 | — | — | CN | disclosed |
| CN-104592059-A | 3-acylhydrazone diphenylurea derivatives as well as preparation method and applications thereof | UNIV QINGDAO AGRICULTURAL | 2015-05-06 | — | — | CN | disclosed |