Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149386 | 0.82 | ALDH1A1 (0.51) | HPGDALDH1A1ALOX12MAPTHTT | |
| SCHEMBL28019755 | 0.79 | LMNA (0.51) | ALDH1A1ALOX12SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29231950 | 0.75 | HPGD (0.66) | HPGDALDH1A1POLBKDM4EALOX12 | |
| SCHEMBL3140037 | 0.75 | HPGD (0.64) | HPGDALDH1A1POLBKDM4EALOX12 | |
| SCHEMBL28014187 | 0.73 | EPHX1 (0.44) | HPGDALDH1A1POLBKDM4EMAPT | |
| SCHEMBL4762283 | 0.72 | HPGD (0.61) | HPGDALDH1A1POLBKDM4ECYP1A2 | |
| SCHEMBL1128274 | 0.71 | HPGD (0.60) | HPGDALDH1A1POLBERCC5FEN1 | |
| SCHEMBL30677293 | 0.71 | HPGD (0.60) | HPGDALDH1A1POLBERCC5FEN1 | |
| SCHEMBL28176461 | 0.71 | ALDH1A1 (0.69) | HPGDALDH1A1POLBKDM4EALOX12 | |
| SCHEMBL29191662 | 0.70 | SMN1; SMN2 (0.62) | HPGDALDH1A1POLBKDM4EALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592059-B | 3-acylhydrazone diphenylurea derivative and its preparation method and application | 青岛农业大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104610142-A | 3-bishydrazide diphenylurea derivative, and preparation method and application of 3-bishydrazide diphenylurea derivative | UNIV QINGDAO AGRICULTURAL | 2015-05-13 | — | — | CN | disclosed |
| CN-104592059-A | 3-acylhydrazone diphenylurea derivatives as well as preparation method and applications thereof | UNIV QINGDAO AGRICULTURAL | 2015-05-06 | — | — | CN | disclosed |