Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014998 | 0.83 | MAPT (0.66) | MAPTRAB9ANPC1CTSSCTSK | |
| SCHEMBL10595799 | 0.83 | POLB (0.73) | MAPTTP53SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11813314 | 0.82 | TP53 (0.68) | MAPTTP53SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18133676 | 0.81 | TOP2A (0.54) | MAPTNPC1CTSSCTSKMEN1 | |
| SCHEMBL28172718 | 0.80 | NR1H4 (0.49) | MAPTFAAHSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8602983 | 0.80 | LMNA (0.74) | TP53SMN1; SMN2RAB9ANPC1LMNA | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.80 | POLB (0.78) | MAPTTP53SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1224023 | 0.80 | TP53 (0.71) | MAPTTP53FAAHSMN1; SMN2RAB9A | |
| SCHEMBL9565608 | 0.80 | FAAH (0.67) | TP53FAAHLMNA | |
| SCHEMBL24472053 | 0.78 | ITGB3 (0.47) | MAPTCTSSCTSKALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961672-A | Synthetic method of tartrate of N-(4-fluorobenzyl)-N-(1-methylpiperidine-4-yl)-N'-(4-isobutoxybenzyl)urea | UNIV SHENYANG PHARMACEUTICAL | 2015-10-07 | — | — | CN | claimed |
| CN-107848972-B | Process for the preparation of N- (4-fluorobenzyl) -N- (1-methylpiperidin-4-yl) -N' - (4- (2-methylpropyloxy) phenylmethyl) urea and its tartrate salt and polymorph C | 阿卡蒂亚药品公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-110156664-A | A kind of synthetic method of piperazine Ma Selin | 常州大学 | 2019-08-23 | — | — | CN | disclosed |