SCHEMBL28014433

SCHEMBL28014433

C1CC2CC12.O=C(O)CCC(=O)OCCC1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
KDM5A P29375 3/20 0.38
PHF8 Q9UPP1 3/20 0.38
KDM2A Q9Y2K7 3/20 0.38
KDM4C Q9H3R0 2/20 0.38
KDM4A O75164 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
KLK7 P49862 1/20 0.37
CASP1 P29466 1/20 0.36
EPHX1 P07099 1/20 0.36
HPGD P15428 2/20 0.35
CYSLTR2 Q9NS75 1/20 0.34
CYSLTR1 Q9Y271 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3571826 0.92 LMNA (0.69) LMNAALDH1A1SMN1; SMN2KDM5APHF8
SCHEMBL10940615 0.84 LMNA (0.55) LMNAALDH1A1SMN1; SMN2KDM5APHF8
SCHEMBL10872593 0.79 SMN1; SMN2 (0.49) LMNASMN1; SMN2KDM5APHF8KDM2A
SCHEMBL15490088 0.78 LMNA (0.50) LMNAALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL7434725 0.78 LMNA (0.50) LMNASMN1; SMN2KDM5APHF8KDM2A
SCHEMBL28087428 0.77 SMN1; SMN2 (0.51) LMNASMN1; SMN2MEN1KMT2AMAPT
SCHEMBL8116783 0.76 LMNA (0.47) LMNAALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL29948344 0.76 ITGB3 (0.49) LMNAALDH1A1
SCHEMBL23080074 0.76 LMNA (0.46) LMNAALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL1866736 0.76 SMN1; SMN2 (0.47) LMNAALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104736627-A Propylene resin composition for retort pouch-packaging film SUN ALLOMER LTD 2015-06-24 CN disclosed