Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571826 | 0.84 | LMNA (0.69) | LMNAKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7433510 | 0.83 | MEN1 (0.44) | LMNAMEN1KMT2AKLK7MAPT | |
| SCHEMBL4171328 | 0.79 | EPHX1 (0.49) | LMNAKDM5APHF8KDM2AKDM4C | |
| SCHEMBL28014433 | 0.78 | LMNA (0.59) | LMNAKDM5APHF8KDM2AKDM4C | |
| SCHEMBL10872593 | 0.77 | SMN1; SMN2 (0.49) | LMNAKDM5APHF8KDM2AKDM4C | |
| SCHEMBL27842415 | 0.77 | EPHX1 (0.49) | LMNAMEN1KMT2AMAPTATM | |
| SCHEMBL10389346 | 0.76 | EPHX1 (0.46) | LMNAKDM5APHF8KDM2AKDM4C | |
| SCHEMBL28087428 | 0.76 | SMN1; SMN2 (0.51) | LMNAMEN1KMT2AMAPTATM | |
| SCHEMBL6019680 | 0.76 | SMN1; SMN2 (0.46) | LMNAKMT2AEPHX1SMN1; SMN2HPGD | |
| SCHEMBL10940615 | 0.76 | LMNA (0.55) | LMNAKDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |