Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 7/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014540 | 0.88 | ALDH1A1 (0.42) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL28013931 | 0.81 | P2RX7 (0.52) | MEN1KMT2AKDM4ECDK2 | |
| SCHEMBL28013866 | 0.77 | CNR2 (0.48) | GAAKDM4E | |
| SCHEMBL28816327 | 0.77 | P2RX7 (0.53) | MEN1KMT2AKDM4EMAPTJAK2 | |
| SCHEMBL3839632 | 0.77 | CDK2 (0.52) | GAAMEN1KMT2ACDK2CDK4 | |
| SCHEMBL28971784 | 0.76 | ALDH1A1 (0.44) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL29970839 | 0.73 | CES2 (0.56) | GAAMEN1KMT2AMAPTITGB2 | |
| SCHEMBL27995074 | 0.71 | JAK2 (0.40) | GAAMEN1KMT2AKDM4EJAK2 | |
| SCHEMBL1127907 | 0.71 | CES2 (0.56) | GAAMEN1KMT2AMAPTJAK2 | |
| SCHEMBL25051950 | 0.71 | GAA (0.63) | GAAMEN1KMT2AMAPTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744358-A | Pyridine formylhydrazine compounds with insecticidal activity and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2015-07-01 | — | — | CN | claimed |
| CN-104744358-A | Pyridine formylhydrazine compounds with insecticidal activity and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2015-07-01 | — | — | CN | disclosed |