Benzamide

Benzamide

SCHEMBL28014725

CCO[Si](C)(CCCO)OCC.NC(=O)c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 3/20 0.44
PARP10 Q53GL7 5/20 0.41
KMT2A Q03164 3/20 0.39
PLA2G10 O15496 1/20 0.38
PLA2G2A P14555 1/20 0.38
MEN1 O00255 2/20 0.38
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL28065762 0.82 TSHR (0.35) TDP1CYP3A4TSHRALDH1A1KMT2A
Urea SCHEMBL28099444 0.81 ALOX15 (0.33) CYP4F2CYP4A11
Acetamide SCHEMBL28014727 0.80 ALOX15 (0.32) BLMPMP22CYP4F2CYP4A11LMNA
SCHEMBL692446 0.76 ALDH1A1 (0.35) TSHRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL7216069 0.75 TDP1 (0.60) TDP1L3MBTL1CYP3A4TSHRCYP2C19
SCHEMBL7151943 0.74 NAAA (0.61) POLBLMNANPC1NAAA
Benzamide SCHEMBL1637053 0.74 PARP1 (0.76) MAPTTDP1L3MBTL1POLBCYP3A4
SCHEMBL28872477 0.74 ALDH1A1 (0.33) TSHRHSD17B10ALDH1A1KMT2AMEN1
Water SCHEMBL28128863 0.74 ALDH1A1 (0.33) TSHRHSD17B10ALDH1A1KMT2AMEN1
Phosphine SCHEMBL28031045 0.74 ALDH1A1 (0.33) TSHRHSD17B10ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102786691-B Oil resistance silicon resin composition containing acylamino and preparation method of oil resistance silicon resin composition BLUE STAR CHENGDU NEW MATERIAL CO LTD 2015-05-20 CN disclosed