Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014777 | 1.00 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL1514880 | 0.93 | SLC6A9 (0.34) | — | |
| SCHEMBL1514825 | 0.90 | SLC6A9 (0.36) | — | |
| SCHEMBL1514789 | 0.84 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL1515020 | 0.81 | AR (0.34) | — | |
| SCHEMBL1514823 | 0.81 | JAK2 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL2316400 | 0.80 | — | — | |
| SCHEMBL1514974 | 0.73 | LCK (0.36) | — | |
| SCHEMBL28014793 | 0.71 | SLC6A9 (0.40) | — | |
| SCHEMBL28014792 | 0.71 | SLC6A9 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482203-B | Carbocyclic GLYT1 receptor antagonists | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | claimed |
| CN-102482203-B | Carbocyclic GLYT1 receptor antagonists | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |