Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | YWHAG | P61981 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014793 | 1.00 | SLC6A9 (0.40) | SLC6A9ARGFERKDM4EMEN1 | |
| SCHEMBL28015407 | 0.81 | HTR1A (0.36) | — | |
| SCHEMBL28819152 | 0.79 | HTR1A (0.41) | — | |
| SCHEMBL28819153 | 0.79 | HTR1A (0.41) | — | |
| SCHEMBL1514789 | 0.78 | NOS3 (0.41) | KDM4EHSD17B10 | |
| SCHEMBL1514823 | 0.76 | JAK2 (0.41) | MEN1KMT2A | |
| SCHEMBL28015404 | 0.74 | HRH3 (0.53) | — | |
| SCHEMBL1514880 | 0.72 | SLC6A9 (0.34) | SLC6A9 | |
| SCHEMBL28014778 | 0.71 | NOS3 (0.36) | — | |
| SCHEMBL28014777 | 0.71 | NOS3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482203-B | Carbocyclic GLYT1 receptor antagonists | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |