Methylamine

Methylamine

SCHEMBL28015012

CN.Fc1ccc(Cl)c(F)c1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
SLC6A4 P31645 3/20 0.42
HTR2A P28223 1/20 0.42
KCNH2 Q12809 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.40
IDO1 P14902 2/20 0.39
AGXT P21549 2/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
SLC6A3 Q01959 3/20 0.38
TRPA1 O75762 1/20 0.37
CA3 P07451 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
HTR7 P34969 1/20 0.36
DPP4 P27487 1/20 0.36
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415157 0.92
SCHEMBL168149 0.92
Hydrogen Sulfide SCHEMBL28281008 0.90 ALDH1A1 (0.46) ALDH1A1SLC6A4HTR2AKCNH2RAPGEF4
Hydrochloric Acid SCHEMBL27672354 0.90 ALDH1A1 (0.46) ALDH1A1SLC6A4HTR2AKCNH2RAPGEF4
SCHEMBL10672634 0.90 ALDH1A1 (0.46) ALDH1A1SLC6A4HTR2AKCNH2RAPGEF4
Phosphine SCHEMBL28192227 0.90 ALDH1A1 (0.46) ALDH1A1SLC6A4HTR2AKCNH2RAPGEF4
Formaldehyde SCHEMBL27818197 0.85 CES2 (0.43) ALDH1A1SLC6A4HTR2AKCNH2RAPGEF4
Formamide SCHEMBL28233113 0.84 ALDH1A1 (0.43) ALDH1A1SLC6A4HTR2AKCNH2IDO1
SCHEMBL27594919 0.81 PSEN1 (0.41) ALDH1A1SLC6A4HTR2AKCNH2CES2
SCHEMBL28172707 0.81 HTR2A (0.41) ALDH1A1SLC6A4HTR2AKCNH2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104620104-B Affinity Reagents for Protein Purification 非凡食品有限公司 2017-03-01 CN claimed
CN-104620104-B Affinity Reagents for Protein Purification 非凡食品有限公司 2017-03-01 CN disclosed
CN-104620104-A Affinity Reagents for Protein Purification MARAXI INC 2015-05-13 CN disclosed