Formamide

Formamide

SCHEMBL28233113

Fc1ccc(Cl)c(F)c1.NC=O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
KCNH2 Q12809 1/20 0.36
KCNQ3 O43525 1/20 0.36
KCNQ2 O43526 1/20 0.36
KCNE1 P15382 1/20 0.36
KCNQ1 P51787 1/20 0.36
KCNQ5 Q9NR82 1/20 0.36
NFE2L2 Q16236 2/20 0.35
IDO1 P14902 2/20 0.35
AGXT P21549 2/20 0.35
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172707 0.89 HTR2A (0.41) ALDH1A1ATMTDP1CES2CES1
Formic Acid SCHEMBL27372403 0.87 CES2 (0.43) ALDH1A1ATMTDP1CES2CES1
SCHEMBL168149 0.86
SCHEMBL29415157 0.86
Formaldehyde SCHEMBL27818197 0.84 CES2 (0.43) ALDH1A1ATMTDP1CES2CES1
Methylamine SCHEMBL28015012 0.84 ALDH1A1 (0.48) ALDH1A1ATMTDP1CES2CES1
SCHEMBL10672634 0.84 ALDH1A1 (0.46) ALDH1A1ATMTDP1CES2CES1
Phosphine SCHEMBL28192227 0.84 ALDH1A1 (0.46) ALDH1A1ATMTDP1CES2CES1
Hydrogen Sulfide SCHEMBL28281008 0.84 ALDH1A1 (0.46) ALDH1A1ATMTDP1CES2CES1
Hydrochloric Acid SCHEMBL27672354 0.84 ALDH1A1 (0.46) ALDH1A1ATMTDP1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104718188-B The benzamides of N- substitutions and its purposes in treating pain 基因泰克公司 2018-08-21 CN disclosed