Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089858 | 0.87 | RAB9A (0.54) | TSPOCYP2C19ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL2093212 | 0.84 | CYP2C19 (0.59) | TSPOCYP2C19ALDH1A1L3MBTL1TSHR | |
| SCHEMBL5544416 | 0.83 | TSPO (0.44) | TSPOCYP2C19ALDH1A1L3MBTL1TSHR | |
| SCHEMBL305633 | 0.81 | TSHR (0.45) | CYP2C19ALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2088915 | 0.79 | ATF1 (0.39) | TSPOALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2090652 | 0.79 | L3MBTL1 (0.37) | TSPOALDH1A1L3MBTL1TSHRNR3C1 | |
| SCHEMBL2097236 | 0.78 | TDP1 (0.38) | TSPOALDH1A1L3MBTL1RAB9AHTT | |
| SCHEMBL2091245 | 0.78 | S1PR1 (0.39) | TSPOALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL27787417 | 0.77 | MAOB (0.44) | CYP2C19ALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2092014 | 0.76 | S1PR1 (0.45) | TSPOCYP2C19ALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |