SCHEMBL28015271

SCHEMBL28015271

CS(=O)(=O)Nc1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PGR P06401 12/20 1.00
HPGD P15428 2/20 0.67
HTT P42858 2/20 0.67
KEAP1 Q14145 1/20 0.67
NPC1 O15118 1/20 0.63
AR P10275 1/20 0.63
RAB9A P51151 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
FFAR1 O14842 2/20 0.61
FFAR4 Q5NUL3 1/20 0.57
NR3C2 P08235 2/20 0.56
GAA P10253 1/20 0.55
TSHR P16473 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376915 0.95 PGR (0.90) PGRHPGDHTTKEAP1NPC1
SCHEMBL4205144 0.92 PGR (0.85) PGRHPGDHTTKEAP1NPC1
SCHEMBL12172176 0.92 PGR (0.84) PGRHPGDHTTKEAP1NPC1
SCHEMBL3112491 0.85 PGR (0.73) PGRHPGDHTTKEAP1NPC1
SCHEMBL3116450 0.85 PGR (0.73) PGRHPGDHTTKEAP1NPC1
SCHEMBL28178583 0.84 PGR (0.72) PGRHTTKEAP1SMN1; SMN2
SCHEMBL2451476 0.83 PGR (0.71) PGRHPGDHTTKEAP1NPC1
SCHEMBL3314859 0.83 PGR (0.71) PGRHPGDHTTKEAP1NPC1
SCHEMBL56693 0.81 KEAP1 (1.00) PGRHPGDHTTKEAP1NPC1
SCHEMBL7263671 0.81 PGR (0.68) PGRHPGDHTTFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104769021-B Flexible device substrate, flexible device and its manufacture method, laminate and its manufacture method and resin combination 旭化成株式会社 2017-10-10 CN disclosed
CN-104769021-A Substrate for flexible device, flexible device and method for producing same, laminate and method for producing same, and resin composition ASAHI KASEI E MATERIALS CORP 2015-07-08 CN disclosed