SCHEMBL28015286

SCHEMBL28015286

COC(=O)C(Cl)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
ALDH1A1 P00352 3/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
TSHR P16473 4/20 0.43
MEN1 O00255 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28264977 0.83 HPGD (0.46) KMT2AMEN1GAAHPGD
SCHEMBL10763803 0.82 MEN1 (0.40) KMT2AMTNR1AMTNR1BALDH1A1MEN1
SCHEMBL11509321 0.81 TDP1 (0.51) KMT2AMTNR1AMTNR1BALDH1A1CRHBP
Dimethylamine SCHEMBL27771570 0.81 MTNR1A (0.45) KMT2AMTNR1AMTNR1BALDH1A1CRHBP
SCHEMBL11776865 0.80 TSHR (0.42) KMT2AMTNR1AMTNR1BALDH1A1CRHBP
SCHEMBL7852386 0.80 KMT2A (0.53) KMT2AMTNR1AMTNR1BALDH1A1TSHR
SCHEMBL6275712 0.80 MTNR1A (0.47) KMT2AMTNR1AMTNR1BALDH1A1CRHBP
SCHEMBL101519 0.79 PPARG (0.46) KMT2AMTNR1AMTNR1BALDH1A1MEN1
SCHEMBL27647095 0.79 MEN1 (0.45) KMT2AMTNR1AMTNR1BALDH1A1TSHR
SCHEMBL28851258 0.79 ALDH1A1 (0.50) MTNR1AMTNR1BALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104513186-B A kind of preparation method of optically pure dextrorotation Cloprostenol Sodium 宁波第二激素厂 2016-10-05 CN claimed
CN-104513186-A Preparation method of optically pure dextro cloprostenol sodium Ningbo second hormone factory 2015-04-15 CN claimed
CN-108947835-A A kind of preparation method of phenoxy acetic acid ester 山东润博生物科技有限公司 2018-12-07 CN disclosed
CN-108947816-A A kind of preparation method of chloro phenoxy acetic acid ester 山东润博生物科技有限公司 2018-12-07 CN disclosed
CN-104513186-B A kind of preparation method of optically pure dextrorotation Cloprostenol Sodium 宁波第二激素厂 2016-10-05 CN disclosed
CN-104513186-A Preparation method of optically pure dextro cloprostenol sodium Ningbo second hormone factory 2015-04-15 CN disclosed