Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28015893 | 0.86 | SIGMAR1 (0.48) | SIGMAR1MAPTKDM4EKMT2AALDH1A1 | |
| Formaldehyde SCHEMBL28819216 | 0.86 | SIGMAR1 (0.61) | SIGMAR1MAPTKMT2AALDH1A1LMNA | |
| Formaldehyde SCHEMBL28015895 | 0.85 | KCNH2 (0.42) | SIGMAR1DRD2DRD3KCNH2MAPT | |
| SCHEMBL10620662 | 0.81 | SIGMAR1 (0.67) | SIGMAR1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL28252525 | 0.73 | SIGMAR1 (0.44) | SIGMAR1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28252517 | 0.69 | ALDH1A1 (0.49) | SIGMAR1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28293590 | 0.68 | SIGMAR1 (0.67) | SIGMAR1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27931241 | 0.68 | ABCG2 (0.46) | SIGMAR1MAPTGAAKMT2AALDH1A1 | |
| SCHEMBL23018401 | 0.67 | SIGMAR1 (0.41) | SIGMAR1KMT2AALDH1A1LMNACTSD | |
| SCHEMBL6801284 | 0.66 | SIGMAR1 (0.44) | SIGMAR1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744379-A | Quinazolinone compound and synthetic method thereof | UNIV CHINA THREE GORGES CTGU | 2015-07-01 | — | — | CN | disclosed |