Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620662 | 0.77 | SIGMAR1 (0.67) | SIGMAR1CTSDBCHEACHEALDH1A1 | |
| Formaldehyde SCHEMBL28819216 | 0.73 | SIGMAR1 (0.61) | SIGMAR1CTSDBCHEACHEALDH1A1 | |
| SCHEMBL6801284 | 0.71 | SIGMAR1 (0.44) | SIGMAR1CTSDBCHEACHEALDH1A1 | |
| SCHEMBL23018401 | 0.69 | SIGMAR1 (0.41) | SIGMAR1CTSDBCHEACHEALDH1A1 | |
| SCHEMBL9538960 | 0.67 | SIGMAR1 (0.41) | SIGMAR1CCR3CTSDBCHEACHE | |
| SCHEMBL25300297 | 0.66 | DRD2 (0.41) | — | |
| SCHEMBL9541511 | 0.65 | ALDH1A1 (0.41) | SIGMAR1CCR3CTSDBCHEACHE | |
| SCHEMBL3233624 | 0.65 | DRD2 (0.47) | SIGMAR1LMNA | |
| SCHEMBL3212700 | 0.64 | SIGMAR1 (0.46) | SIGMAR1CCR3CTSDBCHEACHE | |
| SCHEMBL7114310 | 0.64 | SIGMAR1 (0.44) | SIGMAR1CCR3CTSDBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822046-A | The method of one pot process quianzolinones | 河南大学 | 2018-11-16 | — | — | CN | disclosed |