SCHEMBL28015366

SCHEMBL28015366

Cn1c(N)c(Br)c(=O)n(C)c1=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 3/20 0.43
POLB P06746 3/20 0.40
HTT P42858 2/20 0.40
MAPT P10636 3/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
ATAD2 Q6PL18 2/20 0.38
HIF1A Q16665 1/20 0.36
PABPC1 P11940 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.34
RXFP1 Q9HBX9 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88218 0.75 ALDH1A1 (0.47) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL15384321 0.73 ALDH1A1 (0.46) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL12169061 0.73 ADORA2A (0.36) ALDH1A1KDM4EPOLBHTTHPGD
Water SCHEMBL3902406 0.73 ALDH1A1 (0.46) ALDH1A1KDM4EGLAKMT2APOLB
Hydrochloric Acid SCHEMBL6316692 0.73 ALDH1A1 (0.46) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL19530909 0.70 ALDH1A1 (0.47) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL1029816 0.68 KMT2A (0.43) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL4193697 0.68 CASP6 (0.66) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL1270581 0.67 ALDH1A1 (0.41) ALDH1A1KDM4EGLAKMT2APOLB
SCHEMBL3798203 0.67 RXFP1 (0.41) ALDH1A1KDM4EGLAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744465-A Synthetic method of high-purity high-yield theophylline HEFEI PINGGUANG PHARMACEUTICAL CO LTD 2015-07-01 CN disclosed