Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546702 | 0.77 | CASP6 (0.50) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL7321137 | 0.77 | CASP6 (0.50) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL1545988 | 0.75 | ALDH1A1 (0.47) | CASP6KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8830896 | 0.74 | GSK3A (0.49) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL4255826 | 0.74 | CASP6 (0.46) | CASP6KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL9326371 | 0.74 | POLB (0.55) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL4809819 | 0.73 | CASP6 (0.45) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL4379829 | 0.73 | ALDH1A1 (0.47) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL3079303 | 0.73 | PDE5A (0.51) | CASP6POLBKMT2AALDH1A1MAPT | |
| SCHEMBL4379825 | 0.73 | ALDH1A1 (0.47) | CASP6POLBKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106046004-A | Total synthesis method for theacrine | 上海佰特因医药科技有限公司 | 2016-10-26 | — | — | CN | claimed |
| EP-0681868-B1 | Carbon containing catalyst support and process for its preparation | KATALEUNA GMBH CATALYSTS (DE) | 2003-07-30 | — | — | EP | claimed |
| US-5510484-A | Process for preparing 1,3-dimethy-4,5-diaminouracil | BOEHRINGER INGELHEIM KG (DE) | 1996-04-23 | — | — | US | claimed |
| EP-0681868-A1 | Carbon containing catalyst support and process for its preparation | LEUNA-Katalysatoren GmbH (DE) | 1995-11-15 | — | — | EP | claimed |
| EP-0619310-A1 | Improved process for the preparation of 1,3-dimethyl-4,5-diamino-uracil | BOEHRINGER INGELHEIM KG (DE) | 1994-10-12 | — | — | EP | claimed |
| CN-118908901-A | Method for continuously synthesizing aminophylline intermediate 2 through nitrosation | 台州普渡机械设备有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-12054768-B2 | Methods for detecting agglutination and compositions for use in practicing the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-08-06 | — | — | US | disclosed |
| US-20240109892-A1 | POLY(ADP-RIBOSE) GLYCOHYDROLASE (PARG) INHIBITORS AGAINST COVID MACRODOMAIN AND METHODS OF USING THE SAME | NATIONAL INSTITUTES OF HEALTH | 2024-04-04 | — | — | US | disclosed |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| CN-111072574-B | 5, 6-diamino-1, 3-dialkyl substituted uracil and its preparation method | 广东工业大学 | 2023-03-14 | — | — | CN | disclosed |
| EP-4123031-A1 | METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME | The Regents of The University of California (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2022159818-A1 | POLY(ADP-RIBOSE) GLYCOHYDROLASE (PARG) INHIBITORS AGAINST COVID MACRODOMAIN AND METHODS OF USING THE SAME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-07-28 | — | — | WO | disclosed |
| EP-0586523-A4 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | UNIV YALE (US) | 1995-11-29 | — | — | EP | disclosed |
| EP-0681868-A1 | Carbon containing catalyst support and process for its preparation | LEUNA-Katalysatoren GmbH (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0681868-A1 | Carbon containing catalyst support and process for its preparation | LEUNA-Katalysatoren GmbH (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0619310-A1 | Improved process for the preparation of 1,3-dimethyl-4,5-diamino-uracil | BOEHRINGER INGELHEIM KG (DE) | 1994-10-12 | — | — | EP | disclosed |
| EP-0619310-A1 | Improved process for the preparation of 1,3-dimethyl-4,5-diamino-uracil | BOEHRINGER INGELHEIM KG (DE) | 1994-10-12 | — | — | EP | disclosed |
| EP-0586523-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5213972-A | Production of thymidine and deoxyuridine, intermediates for AZT | CHEMGEN CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109892-A1 | POLY(ADP-RIBOSE) GLYCOHYDROLASE (PARG) INHIBITORS AGAINST COVID MACRODOMAIN AND METHODS OF USING THE SAME | MACROD2, MACROD1, PARG | CASP6 1529/4885POLB 621/4885KMT2A 1290/4885 |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | SOD1, ME3, ME2 | CASP6 3710/4885POLB 195/4885KMT2A 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.