Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015713 | 0.89 | PDE5A (0.38) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL20604275 | 0.85 | TLR8 (0.45) | TLR8LMNASMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL20604271 | 0.85 | TLR8 (0.45) | TLR8LMNASMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL5543074 | 0.81 | PTGS2 (0.40) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL5543072 | 0.81 | PTGS2 (0.40) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8379850 | 0.81 | LMNA (0.41) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL5541843 | 0.79 | PTGS2 (0.38) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL5541838 | 0.79 | PTGS2 (0.38) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8206128 | 0.78 | TLR8 (0.51) | TLR8LMNAMEN1KMT2ATYMP | |
| SCHEMBL5542399 | 0.77 | PTGS2 (0.38) | PTGS2LMNASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |