SCHEMBL20604271

SCHEMBL20604271

CCC/C=C/c1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.45
CHAT P28329 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.43
NFE2L2 Q16236 4/20 0.43
CYP1A2 P05177 2/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
RELA Q04206 1/20 0.43
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
GSR P00390 1/20 0.41
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20604275 1.00 TLR8 (0.45) TLR8CHATSMN1; SMN2HPGDLMNA
SCHEMBL10323297 0.89 CHAT (0.42) CHATSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL3437033 0.89 CHAT (0.42) CHATSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL11652547 0.85 CYSLTR2 (0.47) CHATSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL11652543 0.85 CYSLTR2 (0.47) CHATSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL8206128 0.85 TLR8 (0.51) TLR8LMNANFE2L2MEN1KMT2A
SCHEMBL28015702 0.85 PTGS2 (0.40) TLR8SMN1; SMN2LMNAALDH1A1HDAC1
SCHEMBL29528779 0.83 CHAT (0.47) CHATSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL256666 0.83 CHAT (0.47) CHATSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL6568108 0.83 CHAT (0.47) CHATSMN1; SMN2HPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
CN-109071424-B Sulfamate derivative compound, preparation method and application thereof 生物药品解决方案有限公司 2022-01-14 CN disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
EP-3423433-A1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES Bio-Pharm Solutions Co., Ltd. (KR) 2019-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses STS, SULT2A1, SULT1A1 TLR8 2117/4885CHAT 706/4885SMN1; SMN2 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.