Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556871 | 0.83 | MEN1 (0.41) | NR1H2NR1H3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28015066 | 0.81 | MEN1 (0.41) | MEN1KMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL10159871 | 0.79 | CA12 (0.44) | NR1H2NR1H3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4892428 | 0.76 | CA12 (0.43) | NR1H2NR1H3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6699279 | 0.75 | TAAR1 (0.45) | MEN1KMT2ASMN1; SMN2CA12CA2 | |
| SCHEMBL27629539 | 0.73 | CARM1 (0.47) | SMN1; SMN2CA12CA9CYP3A4ALDH1A1 | |
| SCHEMBL6258041 | 0.72 | CA12 (0.42) | NR1H2NR1H3MEN1KMT2ACA12 | |
| SCHEMBL10547015 | 0.72 | SMN1; SMN2 (0.43) | NR1H2NR1H3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22781056 | 0.71 | SIGMAR1 (0.37) | MEN1KMT2ASMN1; SMN2CA12CA2 | |
| SCHEMBL28131828 | 0.69 | NR1H3 (0.44) | NR1H2NR1H3MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |