Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556871 | 0.79 | MEN1 (0.41) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL10159871 | 0.79 | CA12 (0.44) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL22537753 | 0.77 | CA12 (0.37) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL28015704 | 0.76 | NR1H2 (0.39) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL14481321 | 0.75 | KMT2A (0.44) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL6699279 | 0.75 | TAAR1 (0.45) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL22431448 | 0.74 | CA12 (0.35) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL22781056 | 0.74 | SIGMAR1 (0.37) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL7741833 | 0.73 | CA12 (0.47) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL7270829 | 0.73 | CARM1 (0.47) | CA12CA9CYP3A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-0106055-B1 | PROCESS FOR THE PREPARATION OF CARBAMIC ACID ESTERS | BASF Aktiengesellschaft (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4537960-A | REACTING UREA WITH AN AMINOPROPANOL | BASF AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |
| EP-0106055-A2 | Process for the preparation of carbamic acid esters | BASF Aktiengesellschaft (DE) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | KRT18, CDC73, TYR | CA12 1707/4885CA2 2754/4885CA9 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.