Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819206 | 0.89 | ALDH1A1 (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL17103626 | 0.84 | MEN1 (0.56) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL26758017 | 0.81 | ALDH1A1 (0.67) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL1986154 | 0.80 | KMT2A (0.74) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL4118579 | 0.76 | KMT2A (0.72) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL13265784 | 0.75 | FFAR1 (0.55) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL27592746 | 0.75 | RAB9A (0.61) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL3638667 | 0.75 | JAK2 (0.64) | KMT2AMEN1MAPTSMN1; SMN2HPGD | |
| SCHEMBL4254145 | 0.74 | MEN1 (0.80) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL3737969 | 0.74 | MEN1 (0.73) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183625-B | Anti-HIV compound and preparation method and application thereof | UNIV SICHUAN | 2015-07-08 | — | — | CN | disclosed |