Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926087 | 0.87 | DPP4 (0.41) | BPTFKAT2BDPP4HIF1APRMT5 | |
| SCHEMBL9957742 | 0.80 | HIF1A (0.41) | HIF1AKMT2APKMBRD4KDM4E | |
| SCHEMBL9957146 | 0.76 | LPAR1 (0.45) | HIF1AKMT2APKMKDM4EMAPT | |
| SCHEMBL9956957 | 0.75 | HIF1A (0.41) | HIF1AKMT2APKMBRD4BRD9 | |
| SCHEMBL16003830 | 0.68 | PDE10A (0.47) | KDM4E | |
| SCHEMBL22609479 | 0.67 | GABRA1 (0.39) | BPTFKAT2BKMT2AGAA | |
| SCHEMBL3787333 | 0.67 | DPP4 (0.73) | DPP4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9957126 | 0.66 | KDM4E (0.43) | HIF1AKMT2APKMBRD4KDM4E | |
| SCHEMBL27945135 | 0.66 | LMNA (0.38) | PKMMAPT | |
| SCHEMBL9957150 | 0.66 | MAPKAPK2 (0.45) | KMT2APKMKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402977-B | Ingenol-3-acylate III and ingenol-3-carbamate | LEO PHARMA A/S (IE) | 2016-01-20 | — | — | CN | disclosed |
| CN-104529827-A | Ingenol-3-acylates III and ingenol-3-carbamates | LEO PHARMA AS | 2015-04-22 | — | — | CN | disclosed |
| CN-103402977-A | Ingenol-3-acylate III and Ingenol-3-carbamate | LEO PHARMA AS | 2013-11-20 | — | — | CN | disclosed |