Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234983 | 0.89 | POLB (0.48) | POLBCSNK2A1CLCN2ACLYPPARG | |
| SCHEMBL336771 | 0.83 | SMN1; SMN2 (0.63) | CSNK2A1CLCN2ACLYPPARGPPARA | |
| SCHEMBL9558834 | 0.81 | TSHR (0.68) | ACLYPPARGPPARAAKR1C2AKR1C1 | |
| SCHEMBL9645033 | 0.80 | CA1 (0.52) | AKR1C2AKR1C1TP53TSHRALDH1A1 | |
| SCHEMBL1712448 | 0.79 | GAA (0.54) | POLBEIF4ETP53TSHRALDH1A1 | |
| SCHEMBL28016199 | 0.76 | ALDH1A1 (0.55) | PPARGPPARAAKR1C2AKR1C1TP53 | |
| SCHEMBL10838195 | 0.76 | POLB (0.48) | POLBCSNK2A1ACLYALDH1A1SMN1; SMN2 | |
| SCHEMBL27738744 | 0.76 | SORT1 (0.42) | CLCN2ACLYALDH1A1MYCNR4A1 | |
| SCHEMBL306765 | 0.75 | ALDH1A1 (0.63) | POLBCSNK2A1CLCN2PPARGPPARA | |
| SCHEMBL25263132 | 0.74 | KDM4E (0.57) | POLBCSNK2A1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329443-A | Process for polyester-carbonate transesterifications | GENERAL ELECTRIC COMPANY (US) | 1982-05-11 | — | — | US | disclosed |