Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 4/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759019 | 0.76 | KMT2A (0.51) | HTTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14769150 | 0.76 | RXFP1 (0.52) | HPGDALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10167973 | 0.76 | NFKB1 (0.52) | JUNNFKB1NFKB2RELA | |
| SCHEMBL4760382 | 0.75 | NFKB1 (0.56) | JUNNFKB1NFKB2RELAMAPT | |
| SCHEMBL5570021 | 0.74 | NFKB1 (0.54) | JUNNFKB1NFKB2RELA | |
| SCHEMBL12519684 | 0.73 | HPGD (0.54) | HPGDALDH1A1SMN1; SMN2LMNAEGLN1 | |
| SCHEMBL6990873 | 0.73 | NFKB1 (0.57) | JUNNFKB1NFKB2RELALMNA | |
| SCHEMBL8544541 | 0.73 | JUN (0.67) | JUNNFKB1NFKB2RELAHPGD | |
| SCHEMBL30498347 | 0.72 | NFKB1 (0.49) | JUNNFKB1NFKB2RELA | |
| SCHEMBL28139992 | 0.70 | P2RX7 (0.57) | HTTHPGDALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650045-A | Preparation method of avanafil | SUZHOU WANGSHAN WANGSHUI BIOMEDICAL CO LTD | 2015-05-27 | — | — | CN | disclosed |