Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935465 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4201170 | 0.85 | ALDH1A1 (0.37) | TRIM24TRIM33P2RX7NPC1ALDH1A1 | |
| Thiophene SCHEMBL29976406 | 0.77 | TRIM24 (0.32) | TRIM24TRIM33P2RX7NPC1ALDH1A1 | |
| SCHEMBL312449 | 0.75 | — | — | |
| SCHEMBL29948333 | 0.75 | — | — | |
| Formic Acid Methyl Ester SCHEMBL29281000 | 0.75 | TRIM24 (0.40) | TRIM24TRIM33NFE2L2P2RX7ERN1 | |
| Iodide SCHEMBL27800728 | 0.74 | TRIM24 (0.55) | TRIM24TRIM33NFE2L2P2RX7ERN1 | |
| Bromide SCHEMBL27551706 | 0.74 | TRIM24 (0.55) | TRIM24TRIM33NFE2L2P2RX7ERN1 | |
| SCHEMBL28007124 | 0.73 | P2RX7 (0.36) | TRIM24TRIM33P2RX7ERN1NPC1 | |
| SCHEMBL25270872 | 0.73 | NFE2L2 (0.36) | TRIM24TRIM33NFE2L2P2RX7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103002735-B | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2015-05-20 | — | — | CN | disclosed |