Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790315 | 0.82 | ACMSD (0.49) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL7536670 | 0.81 | CHRNB2 (0.36) | KDM4EALDH1A1HPGDHSD17B10MMP2 | |
| SCHEMBL300805 | 0.81 | ACMSD (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10790290 | 0.81 | ACMSD (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10790137 | 0.81 | ACMSD (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL31011018 | 0.81 | ACMSD (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9403931 | 0.81 | ACMSD (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL30689750 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL28034437 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL126618 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768525-B | Cosmetic composition and the method for suppressing melanin genesis | 宝洁公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-104780897-A | COSMETIC COMPOSITIONS AND METHODS FOR INHIBITING MELANIN SYNTHESIS | PROCTER & GAMBLE | 2015-07-15 | — | — | CN | disclosed |
| CN-104768525-A | Cosmetic compositions and methods for inhibiting melanin synthesis | PROCTER & GAMBLE | 2015-07-08 | — | — | CN | disclosed |