Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116338 | 0.86 | ERCC5 (0.61) | ERCC5FEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3406445 | 0.77 | ERCC5 (0.46) | ERCC5FEN1ALDH1A1KMT2ASMN1; SMN2 | |
| Chlorobenzene SCHEMBL28138967 | 0.77 | ALDH1A1 (0.54) | MRGPRX4ALDH1A1KMT2AMEN1KDM4E | |
| Tert-Butylamine SCHEMBL3326036 | 0.76 | PARP1 (0.50) | ERCC5FEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27544556 | 0.76 | MYC (0.52) | MRGPRX4ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL18184926 | 0.74 | ERCC5 (0.56) | ERCC5FEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8020335 | 0.73 | SLC6A2 (0.50) | ERCC5FEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16950997 | 0.73 | ERCC5 (0.49) | ERCC5FEN1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28035546 | 0.73 | TSHR (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL4667454 | 0.73 | CA12 (0.52) | MRGPRX4KMT2ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710256-A | Cheap and efficient synthesis method of alpha-hydroxyketone compound | UNIV BEIJING | 2015-06-17 | — | — | CN | claimed |
| CN-104710256-A | Cheap and efficient synthesis method of alpha-hydroxyketone compound | UNIV BEIJING | 2015-06-17 | — | — | CN | disclosed |