Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.61 |
| ▸ | FEN1 | P39748 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylamine SCHEMBL3326036 | 0.88 | PARP1 (0.50) | ERCC5FEN1PARP1ALDH1A1HPGD | |
| SCHEMBL18184926 | 0.87 | ERCC5 (0.56) | ERCC5FEN1PARP1ALDH1A1HPGD | |
| SCHEMBL28016993 | 0.86 | ERCC5 (0.51) | ERCC5FEN1PARP1ALDH1A1HPGD | |
| SCHEMBL8020335 | 0.86 | SLC6A2 (0.50) | ERCC5FEN1PARP1ALDH1A1HPGD | |
| SCHEMBL14982193 | 0.85 | ERCC5 (0.63) | ERCC5FEN1PARP1ALDH1A1HPGD | |
| SCHEMBL10389972 | 0.85 | SMN1; SMN2 (0.54) | ALDH1A1HPGDMAPTGAAHTT | |
| SCHEMBL634434 | 0.85 | ERCC5 (0.57) | ERCC5FEN1PARP1ALDH1A1HPGD | |
| SCHEMBL11791699 | 0.83 | ERCC5 (0.76) | ERCC5FEN1PARP1HPGDMAPT | |
| SCHEMBL29962144 | 0.83 | ERCC5 (0.76) | ERCC5FEN1PARP1HPGDMAPT | |
| SCHEMBL3406445 | 0.83 | ERCC5 (0.46) | ERCC5FEN1PARP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1098 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954624-A | Method for efficiently synthesizing 3-chloro-propiophenone | 山东极地医药科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-118685463-B | Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies | 杭州微远生物科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119595791-A | Detection and analysis method for mutation-causing impurities in tomoxetine hydrochloride key starting material 3-chloropropanol | 植恩生物技术股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-118771958-A | Preparation method of R- (+) -3-chloropropanol | 山东省药学科学院 | 2024-10-15 | — | — | CN | claimed |
| CN-118685463-A | Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies | 杭州微远生物科技有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-114193867-B | Preparation method of asphalt-based pre-laid waterproof coiled material | 唐山凯伦新材料科技有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117886683-A | Preparation method of m-chloropropiophenone | 山东德澳精细化学品有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117363667-B | Use of imine reductase in preparation of dapoxetine intermediate and/or dapoxetine | 欣雅利华生物技术(上海)有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117451880-A | Method for measuring dapoxetine hydrochloride impurity by using supercritical fluid chromatography | 海南卓力制药有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117363667-A | Use of imine reductase in preparation of dapoxetine intermediate and/or dapoxetine | 欣雅利华生物技术(上海)有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-101088985-A | Amfebutamone hydrochloride synthesizing process | ZHEJIANG PULUO MEDICINE SCI TE (CN) | 2007-12-19 | — | — | CN | claimed |
| EP-1602369-A2 | Bupropion Metabolites and Methods of their Synthesis and Use | Sepracor, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| US-20050096318-A1 | Pharmaceutically active morpholinol | GLAXOSMITHKLINE SPA (IT) | 2005-05-05 | — | — | US | claimed |
| US-6855820-B2 | Pharmaceutically active morpholinol | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-15 | — | — | US | claimed |
| WO-2004024674-A1 | PROCESS FOR THE PREPARATION OF BUPROPION HYDROCHLORIDE | EOS ECZACIBASI OZGUN KIMYASAL URUNLER SANAYI VE TICARET A.S. (TR) | 2004-03-25 | — | — | WO | claimed |
| EP-1259243-A2 | BUPROPION METABOLITES AND METHODS OF THEIR SYNTHESIS AND USE | SEPRACOR, INC. (US) | 2002-11-27 | — | — | EP | claimed |
| US-20020052341-A1 | Bupropion metabolites and methods of their synthesis and use | SEPRACOR INC. | 2002-05-02 | — | — | US | claimed |
| WO-2001062257-A2 | BUPROPION METABOLITES AND METHODS OF THEIR SYNTHESIS AND USE | SEPRACOR INC. (US) | 2001-08-30 | — | — | WO | claimed |
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | claimed |
| EP-0038071-B1 | NEW UNLABELLED AND RADIOACTIVE LABELLED DERIVATIVES OF BUTYLAMINO PROPIOPHENONE, THEIR PREPARATION, IMMUNOGENS OBTAINED FROM THE UNLABELLED DERIVATIVES AND A PROCESS FOR IMMUNOGEN PREPARATION, ANTISERA RAISED USING THE IMMUNOGENS AND A METHOD FOR RAISING ANTISERA, A RADIOIMMUNOASSAY METHOD AND A TEST KIT FOR USE IN THE ASSAY METHOD | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052341-A1 | Bupropion metabolites and methods of their synthesis and use | MAOB, MAOA, HTR5A | ERCC5 1189/4885FEN1 2462/4885PARP1 3069/4885 |
| US-20050096318-A1 | Pharmaceutically active morpholinol | ACHE, COMT, SNCA | ERCC5 3385/4885FEN1 3827/4885PARP1 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.