SCHEMBL28017010

SCHEMBL28017010

Cc1ccc(S(=O)(=O)n2c(-c3ccccc3)cc3cc(C)ccc32)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACLY P53396 10/20 0.61
CA12 O43570 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52
ALDH3A1 P30838 1/20 0.48
AGTR1 P30556 1/20 0.47
NOD2 Q9HC29 2/20 0.46
NOD1 Q9Y239 2/20 0.46
GAA P10253 2/20 0.46
CXCL8 P10145 1/20 0.46
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3560088 0.96 ACLY (0.63) ACLYCA12CA2CA9PPARG
SCHEMBL28017014 0.90 CA12 (0.69) ACLYCA12CA2CA9ALDH3A1
SCHEMBL14953618 0.90 ACLY (0.61) ACLYCA12CA2CA9PPARG
SCHEMBL14953597 0.90 ACLY (0.60) ACLYCA12CA2CA9PPARG
SCHEMBL28411702 0.90 ACLY (0.60) ACLYCA12CA2CA9PPARG
SCHEMBL28529811 0.89 CA2 (0.56) ACLYCA12CA2CA9ALDH3A1
SCHEMBL28016373 0.87 ACLY (0.60) ACLYCA12CA2CA9L3MBTL1
SCHEMBL28525103 0.86 PPARG (0.51) ACLYCA12CA2CA9PPARG
SCHEMBL29597969 0.86 PPARG (0.51) ACLYCA12CA2CA9PPARG
SCHEMBL29597318 0.86 ACLY (0.59) ACLYCA12CA2CA9PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592086-A Method for preparing indole compound through copper salt catalysis UNIV TAIZHOU 2015-05-06 CN claimed
CN-104592086-B A kind of method that Benzazole compounds are prepared by mantoquita catalysis 台州学院 2017-06-06 CN disclosed
CN-104592086-A Method for preparing indole compound through copper salt catalysis UNIV TAIZHOU 2015-05-06 CN disclosed