Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377175 | 0.83 | L3MBTL1 (0.61) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL377609 | 0.83 | L3MBTL1 (0.61) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29903902 | 0.83 | L3MBTL1 (0.61) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL146867 | 0.83 | L3MBTL1 (0.61) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23782080 | 0.81 | L3MBTL1 (0.59) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6739142 | 0.81 | L3MBTL1 (0.59) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10824814 | 0.81 | CYP2C19 (0.55) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4082495 | 0.80 | LMNA (0.48) | CYP2C19POLBCYP2D6SRCLMNA | |
| SCHEMBL12294613 | 0.79 | SMN1; SMN2 (0.54) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9668117 | 0.79 | CYP2C19 (0.53) | CYP2C19POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104718200-A | Thiophene derivatives used in the treatment of diabetes | METABRAIN RES | 2015-06-17 | — | — | CN | disclosed |