Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553221 | 0.82 | CTBP2 (0.43) | LMNASMN1; SMN2HIF1ABLMFFAR1 | |
| SCHEMBL5235928 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1ACES2CES1 | |
| SCHEMBL29009993 | 0.80 | SRD5A2 (0.50) | KMT2ARXRARXRBCES2CES1 | |
| SCHEMBL25224016 | 0.80 | PPARG (0.45) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14955258 | 0.77 | S1PR2 (0.48) | KMT2ALMNAL3MBTL1BLM | |
| SCHEMBL12492687 | 0.76 | BLM (0.46) | MEN1KMT2ALMNABLMMME | |
| SCHEMBL5149405 | 0.76 | BLM (0.46) | MEN1KMT2ALMNARXRARXRB | |
| SCHEMBL7810611 | 0.76 | FDPS (0.47) | SMN1; SMN2HIF1A | |
| SCHEMBL27167976 | 0.75 | LMNA (0.46) | MEN1KMT2ALMNASMN1; SMN2CES2 | |
| SCHEMBL2175094 | 0.74 | BLM (0.44) | MEN1KMT2ALMNARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557512-B | A kind of 3-(bromo phenyl)-2, the preparation method of 2 '-difluoro propionic acid | SHANXI UNIVERISTY (CN) | 2016-05-11 | — | — | CN | claimed |
| CN-104557512-A | Preparation method of 3-(bromophenyl)-2,2'-difluoropropanoic acid | UNIV SHANXI | 2015-04-29 | — | — | CN | claimed |
| CN-104557512-B | A kind of 3-(bromo phenyl)-2, the preparation method of 2 '-difluoro propionic acid | SHANXI UNIVERISTY (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-104557512-B | A kind of 3-(bromo phenyl)-2, the preparation method of 2 '-difluoro propionic acid | SHANXI UNIVERISTY (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-104557512-A | Preparation method of 3-(bromophenyl)-2,2'-difluoropropanoic acid | UNIV SHANXI | 2015-04-29 | — | — | CN | disclosed |