SCHEMBL14955258

SCHEMBL14955258

CCCc1ccc(CC(F)(F)C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.48
S1PR4 O95977 1/20 0.48
S1PR1 P21453 1/20 0.48
S1PR3 Q99500 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.46
PLK1 P53350 1/20 0.44
THRB P10828 2/20 0.43
FAAH O00519 1/20 0.42
ALDH1A1 P00352 5/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MCL1 Q07820 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
POLB P06746 2/20 0.40
CTDSP1 Q9GZU7 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
BLM P54132 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021176 0.80 ALDH1A1 (0.42) L3MBTL1PLK1THRBFAAHALDH1A1
SCHEMBL28553221 0.79 CTBP2 (0.43) ALDH1A1HPGDPOLBKDM4EGAA
SCHEMBL5235928 0.78 SMN1; SMN2 (0.57) FAAH
SCHEMBL25224016 0.77 PPARG (0.45) ALDH1A1KMT2ALMNA
SCHEMBL29009993 0.77 SRD5A2 (0.50) KMT2A
SCHEMBL28017183 0.77 MEN1 (0.40) L3MBTL1BLMKMT2ALMNA
SCHEMBL14039531 0.76 LPL (0.45) L3MBTL1PLK1THRBFAAHALDH1A1
SCHEMBL25146519 0.75 MCL1 (0.50) L3MBTL1PLK1THRBALDH1A1MCL1
SCHEMBL14338314 0.75 LPL (0.45) L3MBTL1PLK1THRBFAAHALDH1A1
SCHEMBL29010102 0.74 RIPK1 (0.42) S1PR2S1PR4S1PR1S1PR3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107337581-B Process for preparing difluoroalcohol compounds 三和涂料工业有限公司 2020-12-29 CN disclosed
EP-3239123-B1 METHOD OF PREPARING DIFLUORINATED ALCOHOL COMPOUND SAMHWA PAINTS IND CO LTD (KR) 2020-01-29 EP disclosed
US-10358412-B2 Method of preparing difluorinated alcohol compound SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2019-07-23 US disclosed
US-20170313651-A1 METHOD OF PREPARING DIFLUORINATED ALCOHOL COMPOUND SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2017-11-02 US disclosed
EP-3239123-A1 METHOD OF PREPARING DIFLUORINATED ALCOHOL COMPOUND Samhwa Paints Industries Co., Ltd. (KR) 2017-11-01 EP disclosed
EP-2617701-B1 COMPOUND HAVING PROPYL ETHER AS BONDING GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2016-07-27 EP disclosed
US-8846164-B2 Compound having propyl ether as bonding group, liquid crystal composition thereof and liquid crystal display device thereof JNC CORPORATION (JP) 2014-09-30 US disclosed
EP-2617701-A1 COMPOUND HAVING PROPYL ETHER AS BONDING GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2013-07-24 EP disclosed
US-20130126783-A1 COMPOUND HAVING PROPYL ETHER AS BONDING GROUP, LIQUID CRYSTAL COMPOSITION THEREOF AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JNC PETROCHEMICAL CORPORATION (JP) 2013-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170313651-A1 METHOD OF PREPARING DIFLUORINATED ALCOHOL COMPOUND PFAS, ADH1C, ADH1A S1PR2 1050/4885S1PR4 1158/4885S1PR1 955/4885
US-10358412-B2 Method of preparing difluorinated alcohol compound PFAS, ADH1C, ADH1A S1PR2 1050/4885S1PR4 1158/4885S1PR1 955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.