Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290954 | 0.81 | CRHBP (0.53) | HTTKMT2ACRHBPCRHR2KCNQ2 | |
| SCHEMBL5808285 | 0.81 | CHRM2 (0.50) | TSHRKMT2ACHRM1CHRM2CHRM5 | |
| SCHEMBL2293835 | 0.79 | CYP1A2 (0.47) | HTTTSHRCRHBPCRHR2KCNQ2 | |
| SCHEMBL22087970 | 0.79 | TSHR (0.45) | HTTTSHRKLK7KMT2ACRHBP | |
| SCHEMBL22086920 | 0.79 | POLB (0.50) | HTTTSHRKLK7KMT2ACRHBP | |
| SCHEMBL28017182 | 0.77 | CYP2C19 (0.53) | KMT2AGAAMEN1LMNAPOLB | |
| SCHEMBL2296077 | 0.76 | POLB (0.52) | HTTTSHRKLK7POLB | |
| SCHEMBL9796665 | 0.75 | HTT (0.45) | HTTTSHRKLK7KMT2ACRHBP | |
| SCHEMBL13043605 | 0.75 | HTT (0.42) | HTTKMT2ACRHBPCRHR2KDM4E | |
| SCHEMBL28508582 | 0.74 | ALDH1A1 (0.50) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104718200-A | Thiophene derivatives used in the treatment of diabetes | METABRAIN RES | 2015-06-17 | — | — | CN | disclosed |