Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14369940 | 0.78 | TSHR (0.52) | TSHRHTTPOLBCYP19A1ALDH1A1 | |
| SCHEMBL9164494 | 0.77 | TSHR (0.38) | TSHRHTTPOLBCYP19A1ALDH1A1 | |
| SCHEMBL28132695 | 0.77 | TSHR (0.38) | TSHRHTTPOLBCYP19A1ALDH1A1 | |
| SCHEMBL7928377 | 0.76 | TSHR (0.45) | TSHRHTTPOLBCYP19A1ALDH1A1 | |
| SCHEMBL6978784 | 0.76 | MEN1 (0.55) | TSHRHTTCYP19A1ALDH1A1HPGD | |
| SCHEMBL3607570 | 0.76 | HTT (0.52) | TSHRHTTPOLBCYP19A1ALDH1A1 | |
| SCHEMBL7310925 | 0.74 | TSHR (0.52) | TSHRHTTPOLBCYP19A1ALDH1A1 | |
| SCHEMBL12030880 | 0.73 | ALB (0.43) | HTTPOLBALDH1A1HPGDNPSR1 | |
| SCHEMBL2590567 | 0.73 | FABP4 (0.52) | HTTPOLBALDH1A1HPGDNPSR1 | |
| SCHEMBL11526155 | 0.72 | ALDH1A1 (0.51) | TSHRHTTALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104649867-A | Preparation method of propofol | LIAONING YAOLIAN PHARMACEUTICAL CO LTD | 2015-05-27 | — | — | CN | disclosed |