Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
| ▸ | FABP3 | P05413 | 2/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960756 | 0.86 | GABRA1 (0.57) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL12030880 | 0.81 | ALB (0.43) | FABP4FABP3FABP5TYRALDH1A1 | |
| SCHEMBL841601 | 0.79 | GABRA1 (0.52) | FABP4FABP3FABP5GABRA1TYR | |
| SCHEMBL1711083 | 0.76 | FABP4 (0.47) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL7979463 | 0.76 | TYR (0.43) | FABP4FABP3FABP5TYRALDH1A1 | |
| SCHEMBL7026756 | 0.76 | ERN1 (0.47) | TYRALDH1A1LMNAAKR1B1HTT | |
| Hydrochloric Acid SCHEMBL5516827 | 0.75 | FABP4 (0.50) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL28091181 | 0.74 | TYR (0.57) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL9945901 | 0.74 | TYR (0.41) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL9369688 | 0.74 | FABP4 (0.56) | FABP4FABP3FABP5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PHOSPHOENIX SARL (FR) | 2010-04-22 | — | — | US | claimed |
| EP-1899358-A2 | NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS | Phosphoenix SARL (FR) | 2008-03-19 | — | — | EP | claimed |
| US-7192983-B2 | Improving storage stability by reacting with hydrogen sulfate lithium- containing compound; aspartyl protease inhibitors | G.D. SEARLE & CO. (US) | 2007-03-20 | — | — | US | claimed |
| WO-2006136695-A2 | NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS | PHOSPHOENIX SARL (FR) | 2006-12-28 | — | — | WO | claimed |
| US-20060074247-A1 | N-protected/N-substituted-beta-amino hydroxy sulfonates | G.D. SEARLE & CO. (US) | 2006-04-06 | — | — | US | claimed |
| US-6586627-B1 | Blocking carbocyclic oxo, amines such as 2-(bis(phenylmethyl) amino)-3-phenylpropanal to form 2-(Bis(phenylmethyl)amino)-1-hydroxy-3-phenylpropylsulfonic Acid Salts, having storage stability; chemical intermediates for enzyme inhibitors | G. D. SEARLE & CO. | 2003-07-01 | — | — | US | claimed |
| US-6147253-A | STABILIZED FORM OF N-PROTECTED/N-SUBSTITUTED ALPHA-AMINO ALDEHYDES | G. D. SEARLE & CO. (US) | 2000-11-14 | — | — | US | claimed |
| EP-0861233-B1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | SEARLE & CO (US) | 2000-05-03 | — | — | EP | claimed |
| US-5939587-A | DEBLOCKING, DESALTING, DESULFONATING AND OXIDATING TO ALDEHYDE; STORAGE STABILITY, MATERIALS HANDLING | G. D. SEARLE & COMPANY (US) | 1999-08-17 | — | — | US | claimed |
| US-5847201-A | N-protected/N-substituted-beta-amino hydroxy sulfonates | G.D. SEARLE & CO. (US) | 1998-12-08 | — | — | US | claimed |
| EP-0861233-A1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | G.D. SEARLE & CO. (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997018190-A1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | G.D. SEARLE & CO. (US) | 1997-05-22 | — | — | WO | claimed |
| CN-107690436-B | Method for forming complexes, complexes and use thereof | 庄信万丰股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-9714339-B2 | Rubber composition comprising an epoxy resin and a polyimine hardener | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-07-25 | — | — | US | disclosed |
| US-9663633-B2 | Composition based on natural rubber and on a polyaldimine compound | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-05-30 | — | — | US | disclosed |
| CN-104487503-B | Comprise epoxy resin and the rubber composition of polyimides sclerosing agent | 米其林集团总公司 | 2016-10-26 | — | — | CN | disclosed |
| WO-1995014653-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-06-01 | — | — | WO | disclosed |
| US-4622429-A | ACYLATION OF BENZENES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |
| EP-0064690-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZALDEHYDES | BAYER AG (DE) | 1985-03-13 | — | — | EP | disclosed |
| EP-0064690-A1 | Process for the preparation of substituted benzaldehydes | BAYER AG (DE) | 1982-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PNP, NANP, PHOSPHO1 | FABP4 964/4885FABP3 1062/4885FABP5 1249/4885 |
| US-20060074247-A1 | N-protected/N-substituted-beta-amino hydroxy sulfonates | AANAT, AASDHPPT, ALDH7A1 | FABP4 2391/4885FABP3 902/4885FABP5 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.