Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 4/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.48 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983919 | 0.87 | PARP1 (0.56) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL7263029 | 0.80 | KDM4E (0.66) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL29535139 | 0.80 | KDM4E (0.66) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL4230805 | 0.78 | ALDH1A1 (0.56) | IP6K1KDM4EHSD17B10NPC1ALDH1A1 | |
| SCHEMBL6014177 | 0.77 | TYMS (0.72) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL3115005 | 0.77 | TYMS (0.72) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL31463101 | 0.77 | TYMS (0.72) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL29900526 | 0.77 | TYMS (0.72) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL28637729 | 0.77 | KDM4E (0.62) | IP6K1KDM4EHSD17B10LMNAPARP1 | |
| SCHEMBL5313776 | 0.77 | TYMS (0.72) | IP6K1KDM4EHSD17B10LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803927-B | Chalcone analog of the base containing 2 methyl, 4 oxoquinazolin 6 and its production and use | 首都师范大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-104803927-A | Chalcone analogue containing 2-methyl-4-oxo-quinazoline-6-base, and preparation method and application thereof | UNIV CAPITAL NORMAL | 2015-07-29 | — | — | CN | disclosed |