Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845853 | 0.90 | CYP19A1 (0.44) | ALOX5KDM4ENPC1RAB9AMAPT | |
| SCHEMBL31324900 | 0.90 | CYP19A1 (0.44) | ALOX5KDM4ENPC1RAB9AMAPT | |
| SCHEMBL4824051 | 0.86 | IKBKB (0.46) | KDM4ENPC1RAB9AMAPTGLA | |
| SCHEMBL31324889 | 0.86 | NPC1 (0.47) | ALOX5KDM4ENPC1RAB9ACYP19A1 | |
| SCHEMBL29987215 | 0.85 | IKBKB (0.45) | KDM4ENPC1RAB9AMAPTGLA | |
| SCHEMBL29022729 | 0.82 | NPC1 (0.46) | ALOX5KDM4ENPC1RAB9AMAPT | |
| SCHEMBL3753723 | 0.82 | RAB9A (0.60) | KDM4ENPC1RAB9AMAPTGLA | |
| SCHEMBL27852488 | 0.82 | ALOX5 (0.36) | ALOX5KDM4ENPC1RAB9AMAPT | |
| SCHEMBL29894537 | 0.80 | ALOX5 (0.38) | ALOX5KDM4ENPC1RAB9AMAPT | |
| SCHEMBL1479681 | 0.80 | ALOX5 (0.42) | ALOX5KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023241640-A1 | SMALL MOLECULE INHIBITOR TARGETING DEUBIQUITINATING ENZYMES USP25 AND USP28 | 深圳湾实验室 | 2023-12-21 | — | — | WO | disclosed |
| CN-115246842-A | Small molecule inhibitors targeting deubiquitinases USP25 and USP28 | 深圳湾实验室 | 2022-10-28 | — | — | CN | disclosed |
| CN-109369891-B | Polymers containing basic groups and their use | 广州华睿光电材料有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-105017279-A | Bithienopyridine derivative and preparation method thereof | BEIJING INST TECHNOLOGY | 2015-11-04 | — | — | CN | disclosed |
| CN-105017279-A | Bithienopyridine derivative and preparation method thereof | BEIJING INST TECHNOLOGY | 2015-11-04 | — | — | CN | disclosed |