Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777069 | 0.84 | KDM4E (0.37) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL28187977 | 0.81 | LDHA (0.35) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL3589092 | 0.81 | HTT (0.31) | — | |
| SCHEMBL15346753 | 0.80 | ACE (0.48) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL38157 | 0.78 | — | — | |
| SCHEMBL27890788 | 0.78 | LMNA (0.47) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| Hydrochloric Acid SCHEMBL6338625 | 0.76 | LMNA (0.44) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL27472582 | 0.76 | — | — | |
| SCHEMBL16108845 | 0.75 | EGLN1 (0.41) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL3104959 | 0.75 | TSHR (0.44) | EGLN1KDM4EKDM6BKDM5CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981470-B | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | 拜耳制药股份公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-103476771-B | IL17 and the IFN-γ being used for the treatment of autoimmune inflammation suppresses | 4SC DISCOVERY GMBH (DE) | 2015-12-23 | — | — | CN | disclosed |
| CN-103459385-B | IL17 and the IFN-γ being used for the treatment of autoimmune inflammation suppresses | 4SC DISCOVERY GMBH (DE) | 2015-08-05 | — | — | CN | disclosed |