Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indene SCHEMBL28210934 | 0.82 | CYP2D6 (0.33) | GAAKCNH2HPGDNAMPT | |
| SCHEMBL168928 | 0.82 | CA12 (0.34) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL5617071 | 0.76 | — | — | |
| SCHEMBL28041462 | 0.73 | — | — | |
| SCHEMBL28018023 | 0.73 | CTSV (0.42) | OPRM1AVPR1A | |
| SCHEMBL30770170 | 0.73 | — | — | |
| Methylparaben SCHEMBL29675138 | 0.72 | CA1 (0.47) | MAPK1GAALMNASLC6A2ALDH1A1 | |
| SCHEMBL29353408 | 0.72 | EPHX2 (0.34) | — | |
| SCHEMBL29876681 | 0.72 | EPHX2 (0.34) | — | |
| Valeric Acid SCHEMBL8345226 | 0.69 | ALDH1A1 (0.50) | MAPK1GAALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108186611-A | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-06-22 | — | — | CN | claimed |
| CN-104797245-B | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-05-04 | — | — | CN | claimed |
| CN-103476404-B | Transdermal composition comprising active agent layer and activating agent conversion coating | 帝国制药美国公司 | 2017-09-29 | — | — | CN | claimed |
| CN-104797245-A | Propynylaminoindan transdermal compositions | TEIKOKU PHARMA USA INC | 2015-07-22 | — | — | CN | claimed |
| CN-108186611-A | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-108186611-A | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-108186611-A | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-104797245-B | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-104797245-B | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-104797245-B | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-103476404-B | Transdermal composition comprising active agent layer and activating agent conversion coating | 帝国制药美国公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-104797245-A | Propynylaminoindan transdermal compositions | TEIKOKU PHARMA USA INC | 2015-07-22 | — | — | CN | disclosed |