Valeric Acid

Valeric Acid

SCHEMBL8345226

CCCCC(=O)O.CCCCC(=O)O.c1ccc2c(c1)CCC2

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
AKR1B1 P15121 1/20 0.47
CYP1A2 P05177 1/20 0.46
GPR84 Q9NQS5 7/20 0.45
PPARG P37231 7/20 0.45
PPARD Q03181 7/20 0.45
PPARA Q07869 7/20 0.45
HDAC11 Q96DB2 6/20 0.45
TSHR P16473 4/20 0.45
PTPN1 P18031 3/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
SLC22A8 Q8TCC7 1/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valeric Acid SCHEMBL28776116 1.00 ALDH1A1 (0.50) ALDH1A1LMNAGAACES2CES1
Hexanoate SCHEMBL9453801 0.95 AKR1B1 (0.55) ALDH1A1LMNAGAACES2CES1
Succinic Acid SCHEMBL23581474 0.81 TSHR (0.59) ALDH1A1LMNAGAACYP1A2PPARG
Biphenyl SCHEMBL27377379 0.79 AKR1B1 (0.56) ALDH1A1LMNACES2CES1AKR1B1
Octane SCHEMBL4861483 0.78 TSHR (0.55) ALDH1A1LMNAGAACYP1A2GPR84
Valeric Acid SCHEMBL29375926 0.78 CES2 (0.44) ALDH1A1CES2CES1AKR1B1GPR84
Valeric Acid SCHEMBL1674731 0.78 AKR1B1 (0.74) ALDH1A1LMNAAKR1B1GPR84PPARG
Fluorene SCHEMBL17443012 0.77 AKR1B1 (0.55) ALDH1A1CES2CES1AKR1B1GPR84
Valeric Acid SCHEMBL5691417 0.77 HSD17B3 (0.55) ALDH1A1CES2CES1AKR1B1GPR84
Valeric Acid SCHEMBL6158046 0.77 AKR1B1 (0.54) ALDH1A1CES2CES1AKR1B1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5959159-A UTILIZES A MICROBIAL LIPASE DERIVED FROM CHROMOBACTERIUM VISCOSUM TO CATALYZE THE ENANTIOSELECTIVE AND REGIOSELECTIVE HYDROLYSIS OF THE (S)(-)-ENANTIOMER OF THE RACEMIC MIXTURE TO ITS CORRESPONDING MONOESTER MOLECULAR OPTOELECTRONICS CORPORATION (US) 1999-09-28 US disclosed
WO-1999022015-A1 METHOD FOR PREPARING OPTICALLY ACTIVE 5-HYDROXY-3- (4'-HYDROXYPHENYL)-1, 1,3-TRIMETHYLINDANE MOLECULAR OPTOELECTRONICS CORPORATION (US) 1999-05-06 WO disclosed