Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28288711 | 0.74 | ALDH1A1 (0.39) | MTNR1AMTNR1BCYP1A2CYP2C19 | |
| SCHEMBL28220158 | 0.71 | CES1 (0.41) | MTNR1AMTNR1BCYP1A2CYP2C19 | |
| SCHEMBL28507906 | 0.69 | ALDH1A1 (0.39) | CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27985687 | 0.69 | HDAC1 (0.39) | MTNR1AMTNR1BCYP1A2CYP2D6HDAC1 | |
| SCHEMBL27723868 | 0.69 | CYP1B1 (0.40) | TAAR1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1286537 | 0.66 | CHRNB2 (0.47) | MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL6509810 | 0.66 | CES1 (0.44) | MTNR1AMTNR1BCYP1A2CYP2C19 | |
| SCHEMBL19890716 | 0.65 | MAPT (0.37) | TAAR1SLC6A2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4585844 | 0.64 | RAB9A (0.39) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12192360 | 0.64 | TAAR1 (0.43) | TAAR1SLC6A2SLC6A4SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693065-B | Compound 1-(diphenylmethylene) amino-2-amino-2-methyl propane and its preparation method and application | 山东百诺医药股份有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-104693065-A | New compound 1-(diphenyl methylene) amino-2-amino-2-methylmethane, preparation method and application thereof in Anagliptin synthesis | JINAN BESTCOMM PHARMACEUTICAL R & D CO LTD | 2015-06-10 | — | — | CN | claimed |
| CN-104693065-B | Compound 1-(diphenylmethylene) amino-2-amino-2-methyl propane and its preparation method and application | 山东百诺医药股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-104693065-B | Compound 1-(diphenylmethylene) amino-2-amino-2-methyl propane and its preparation method and application | 山东百诺医药股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-104693065-A | New compound 1-(diphenyl methylene) amino-2-amino-2-methylmethane, preparation method and application thereof in Anagliptin synthesis | JINAN BESTCOMM PHARMACEUTICAL R & D CO LTD | 2015-06-10 | — | — | CN | disclosed |